Journal article

Muscle-specific androgen receptor deletion shows limited actions in myoblasts but not in myofibers in different muscles in vivo

Kesha Rana, Maria WS Chiu, Patricia K Russell, Jarrod P Skinner, Nicole KL Lee, Barbara C Fam, Jeffrey D Zajac, Helen E MacLean

Journal of Molecular Endocrinology | BIOSCIENTIFICA LTD | Published : 2016

DOI: 10.1530/JME-15-0320

Related Projects (1)

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The molecular mechanisms of anabolic androgen actions in skeletal muscle

We are studying the role of male sex hormones, androgens, in controlling muscle function. Muscle wasting occurs in a variety of disorders, i..

Grants

Awarded by NHMRC Project

Awarded by NHMRC Career Development Award

Funding Acknowledgements

This research was supported by NHMRC Project Grant #350334, a Sir Edward Dunlop Medical Research Foundation Grant, and HEM was supported by NHMRC Career Development Award #359226.

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Keywords

Myogenic Regulatory Factors
Myofibrils
Body-Composition
Muscle
Organ Size
Receptors, Androgen
Mice, Knockout
Biomarkers
Organ Specificity
Physical Conditioning, Animal
Endocrinology & Metabolism
Skeletal-Muscle
Myofibers
Gene Expression Regulation
Knockout
Mice
Gene Deletion
Protein-Synthesis
Life Sciences & Biomedicine
Myogenic Differentiation
Strength
Humans
Elderly-Men
Muscles
Androgen Receptor
Testosterone Treatment
Male
Science & Technology
Animals
Myoblasts
Gene
Satellite Cells