Journal article
Early general movements and brain magnetic resonance imaging at term-equivalent age in infants born < 30 weeks' gestation
JE Olsen, NC Brown, AL Eeles, C Einspieler, KJ Lee, DK Thompson, PJ Anderson, JLY Cheong, LW Doyle, AJ Spittle
Early Human Development | ELSEVIER IRELAND LTD | Published : 2016
Abstract
Background Neurodevelopmental assessments and brain magnetic resonance imaging (MRI) at term-equivalent age (TEA) predict developmental outcomes in preterm infants. However, the relationship between neurodevelopment prior to term and cerebral structure is currently unknown. Aims To examine the relationships between General Movements (GMs) assessed from birth to TEA and brain MRI at TEA in infants born < 30 weeks' gestation. Study design Prospective cohort study. GMs (categorised as ‘normal’ or ‘abnormal’) were recorded weekly from birth to 32 weeks, and at 34 and 36 weeks' postmenstrual age. At TEA, GMs were assessed concurrently with brain MRI (using a validated scoring system). Subjects 14..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This study was funded by grants from the National Health and Medical Research Council (Centre of Research Excellence in Newborn Medicine 1060733; Project Grants 1024516 and 1028822, Career Development Fellowship 1108714-AJS, 1085754-DKT and 1053609-KJL; Early Career Fellowship 1053787-JLYC, Senior Research Fellowship 1081288-PJA); Australian Postgraduate Association Scholarship, University of Melbourne (JEO), Murdoch Childrens Research Institute and the Victorian Government's Operational Infrastructure Support Program.