Journal article

Cell death is not essential for caspase-1-mediated interleukin-1 beta activation and secretion

SA Conos, KE Lawlor, DL Vaux, JE Vince, LM Lindqvist

Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2016


Awarded by National Health and Medical Research (Canberra, Australia)

Awarded by Victorian State Government OIS

Funding Acknowledgements

We thank W Cook and J Silke (WEHI) for vectors, M Rashidi (WEHI) for NF-kappa B Thp1 reporter cells, K Schroder (IMB) for the pMIGR retroviral vector and R Lewis (WEHI) for cloning the IL-1 beta vector. This work was supported by National Health and Medical Research (Canberra, Australia) Project grants (1051210, 1101405), fellowships (JEV (1052598); LL (1035502); DLV (1020136)) and Program Grants (461221), and operational infrastructure grants through the Australian Government IRISS and the Victorian State Government OIS (361646). We thank R Crawley for animal care; S Monard and staff for cell sorting; M Hardy for assistance with ELISpots; L Whitehead for assistance with image acquisition.