Journal article
Global and local grey matter reductions in boys with ADHD combined type and ADHD inattentive type
V Vilgis, L Sun, J Chen, TJ Silk, A Vance
Psychiatry Research Neuroimaging | ELSEVIER IRELAND LTD | Published : 2016
Abstract
Attention-deficit/hyperactivity disorder (ADHD) has reliably been associated with global grey matter reductions but local alterations are largely inconsistent with perhaps the exception of the caudate nucleus. The aim of this study was to examine local and global brain volume differences between typically developing children (TD) and children with a diagnosis of ADHD. We also addressed whether these parameters would differ between children with the ADHD-combined type (ADHD-C) and those with the ADHD-inattentive type (ADHD-I). Using an ROI approach caudate volume differences were also examined. 79 boys between the ages of 8 and 17 participated in the study. Of those 33 met diagnostic criteria..
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Awarded by Royal Children's Hospital Foundation
Funding Acknowledgements
This research was conducted within the Academic Child Psychiatry Unit, University of Melbourne, Royal Children's Hospital (clinical research assessments and scans) and the Developmental Imaging research group, Murdoch Childrens Research Institute and the Children's MRI Centre, Royal Children's Hospital, Melbourne, Victoria (imaging analyses). NHMRC project grants 384419 and 569533 provided funds for the data collection. It was also supported by the Murdoch Childrens Research Institute, the Royal Children's Hospital, The Royal Children's Hospital Foundation, Department of Paediatrics The University of Melbourne and the Victorian Government's Operational Infrastructure Support Program. TS was supported by a NHMRC Career Development Award 1004637.