Journal article

Redirected perforin-dependent lysis of colon carcinoma by ex vivo genetically engineered CTL

PK Darcy, NM Haynes, MB Snook, JA Trapani, L Cerruti, SM Jane, MJ Smyth

The Journal of Immunology | AMER ASSOC IMMUNOLOGISTS | Published : 2000

DOI: 10.4049/jimmunol.164.7.3705

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Keywords

Cell Receptor
Interferon-Gamma
Binding Sites
Chimeric Single-Chain
Immunoglobulin Variable Region
Recombinant Fusion Proteins
Carcinoembryonic Antigen
Adoptive Transfer
Humans
Adenocarcinoma
Lymphocyte Count
Cytokines
Tumor Cells, Cultured
Pore Forming Cytotoxic Proteins
Immunoglobulin Fragments
T-Lymphocytes, Cytotoxic
Life Sciences & Biomedicine
Mice
Immunoglobulin
Neoplasm Transplantation
Epitopes, T-Lymphocyte
Mice, Scid
Tumor-Cells
Molecules
Mice, Inbred Balb C
Mice, Inbred C57bl
Antibody
Cytotoxic T-Lymphocytes
Animals
Mice, Knockout
Receptors, Cell Surface
Membrane Glycoproteins
In-Vivo
Colonic Neoplasms
Carrier Proteins
Immunology
Science & Technology
Cytotoxicity, Immunologic
Perforin
Transduction, Genetic
Cell Division