Journal article
Does PET SUV Harmonization Affect PERCIST Response Classification?
Elske Quak, Pierre-Yves Le Roux, Charline Lasnon, Philippe Robin, Michael S Hofman, David Bourhis, Jason Callahan, David S Binns, Cedric Desmonts, Pierre-Yves Salaun, Rodney J Hicks, Nicolas Aide
JOURNAL OF NUCLEAR MEDICINE | SOC NUCLEAR MEDICINE INC | Published : 2016
Abstract
Pre- and posttreatment PET comparative scans should ideally be obtained with identical acquisition and processing, but this is often impractical. The degree to which differing protocols affect PERCIST classification is unclear. This study evaluates the consistency of PERCIST classification across different reconstruction algorithms and whether a proprietary software tool can harmonize SUV estimation sufficiently to provide consistent response classification. METHODS: Eighty-six patients with non-small cell lung cancer, colorectal liver metastases, or metastatic melanoma who were scanned for therapy monitoring purposes were prospectively recruited in this multicenter trial. Pre- and posttreat..
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Funding Acknowledgements
The costs of publication of this article were defrayed in part by the payment of page charges. Therefore, and solely to indicate this fact, this article is hereby marked "advertisement" in accordance with 18 USC section 1734. Prof. Nicolas Aide received a research grant from Siemens Molecular Imaging. No other potential conflict of interest relevant to this article was reported.