Journal article

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70(S6k)

HBJ Jefferies, S Fumagalli, PB Dennis, C Reinhard, RB Pearson, G Thomas

The EMBO Journal | WILEY-BLACKWELL | Published : 1997

DOI: 10.1093/emboj/16.12.3693

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Keywords

Pyrimidines
Messenger-Rna
Recombinant Fusion Proteins
Cell Line, Transformed
Autoantigen-La
Animals
3t3 Cells
Mammalian Protein
Cell Biology
Science & Technology
Protein Biosynthesis
Sirolimus
Ribosomal Protein S6 Kinases
Translational Control
P70(s6k)
Repression
Rna, Messenger
Mitogenesis
Enzyme Inhibitors
Growth
Mice
Mutagenesis
Identification
Transcription
Enzyme Activation
Biochemistry & Molecular Biology
Human Growth Hormone
S6 Phosphorylation
P70 S6 Kinase
Phosphorylation Sites
Humans
Protein-Serine-Threonine Kinases
Drug Resistance
Polyenes
Life Sciences & Biomedicine
Ribosome Biogenesis
Activated Protein-Kinase