Journal article

Progesterone receptor modulates ER alpha action in breast cancer

Hisham Mohammed, I Alasdair Russell, Rory Stark, Oscar M Rueda, Theresa E Hickey, Gerard A Tarulli, Aurelien AA Serandour, Stephen N Birrell, Alejandra Bruna, Amel Saadi, Suraj Menon, James Hadfield, Michelle Pugh, Ganesh V Raj, Gordon D Brown, Clive D'Santos, Jessica LL Robinson, Grace Silva, Rosalind Launchbury, Charles M Perou Show all

Nature | NATURE PUBLISHING GROUP | Published : 2015

University of Melbourne Researchers


Awarded by National Cancer Institute of National Institutes of Health

Awarded by Department of Defense

Awarded by National Health and Medical Research Council of Australia

Awarded by Cancer Australia

Awarded by US Department of Defense Breast Cancer Research Program (BCRP)


Awarded by Cancer Research UK

Awarded by National Institute for Health Research

Funding Acknowledgements

The authors would like to thank S. Leigh-Brown, the staff in the genomic core facility, S. Halim, the proteomic core facility and the bioinformatic core facility at Cancer Research UK. We acknowledge S. Jindal for pathology review, N. Ryan for technical assistance and S. Edwards for statistical analysis with ex vivo culture. The MCF7-LucYFP cells were a kind gift from N. Benaich. We thank H. Gronemeyer for the PR-A and PR-B expressing vectors. We would like to acknowledge the support of the University of Cambridge, Cancer Research UK and Hutchison Whampoa Limited. Research reported in this manuscript was supported by the National Cancer Institute of the National Institutes of Health under award number 5P30CA142543 (to University of Texas Southwestern) and Department of Defense grants W81XWH-12-1-0288-03 (GVR). W.D.T. is supported by grants from the National Health and Medical Research Council of Australia (ID 1008349; ID 1084416) and Cancer Australia (ID 627229) T.E.H. held a Fellowship Award from the US Department of Defense Breast Cancer Research Program (BCRP; W81XWH-11-1-0592) and currently is supported by a Florey Fellowship from the Royal Adelaide Hospital Research Foundation. J.S.C. is supported by an ERC starting grant and an EMBO Young investigator award.