Outcomes of cutaneous squamous cell carcinoma of the head and neck with parotid metastases

Abstract

Introduction: Cutaneous squamous cell carcinoma of the head and neck (cHNSCC) metastatic to the parotid has a moderate risk of recurrence despite multimodality treatment. Immunosuppression is associated with lower rates of long-term cure. Our aim was to review outcomes of current management in a tertiary centre with a view to targeting future strategies. Methods: A retrospective review of clinico-pathological data and outcomes for patients with metastatic cHNSCC involving the parotid gland, undergoing radical surgery and adjuvant radiotherapy during 2000–2014 was conducted. The Kaplan–Meier method was used to determine time-to-event outcomes. Results: One hundred and thirty-two patients met ..