Musculoskeletal and Endocrine Health in Adults With Cerebral Palsy: New Opportunities for Intervention
A Trinh, P Wong, MC Fahey, J Brown, A Churchyard, BJ Strauss, PR Ebeling, PJ Fuller, F Milat
The Journal of Clinical Endocrinology & Metabolism | ENDOCRINE SOC | Published : 2016
CONTEXT: Cerebral palsy (CP) increases fracture risk through diminished ambulation, nutritional deficiencies, and anticonvulsant medication use. Studies examining bone mineral density (BMD) in adults with CP are limited. OBJECTIVE: To examine the relationship between body composition, BMD, and fractures in adults with CP. The effect of functional, nutritional, and endocrine factors on BMD and body composition is also explored. DESIGN: Retrospective cross-sectional study. SETTING AND PARTICIPANTS: Forty-five adults with CP (mean age, 28.3 ± 11.0 years) who had dual-energy x-ray absorptiometry imaging at a single tertiary hospital between 2005 and 2015. RESULTS: Seventeen (38%) had a past hist..View full abstract
Awarded by National Health and Medical Research Council of Australia, Senior Principal Research Fellowship
A.T. is supported by a Royal Australasian College of Physicians/Osteoporosis Australia Research Grant. F.M. is supported by an Osteoporosis Australia/Australia and New Zealand Bone and Mineral Society Clinical Grant. P.J.F. is supported by a National Health and Medical Research Council of Australia, Senior Principal Research Fellowship (Grant 1002559). Hudson Institute is supported by the Victorian Government's Operational Infrastructure Support program.