A mixed-methods evaluation of adherence to preventive treatment among child tuberculosis contacts in Indonesia

Abstract

BACKGROUND: Tuberculosis (TB) can be prevented using isoniazid preventive therapy (IPT) among child contacts. However, the benefits of IPT depend on adherence to at least 6 months of daily treatment. A greater understanding of the barriers to and facilitators of adherence to IPT in resource-poor settings is required to optimise the benefits. METHODS : We prospectively evaluated adherence to IPT and its associated factors among child contacts (age 0-5 years) eligible for IPT. We undertook in-depth interviews with care givers and a focus group discussion with health careworkers,whichwere thematically analysed to explore barriers to and facilitators of adherence from the perspective of both car..