Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015

H Wang; TM Wolock; A Carter; G Nguyen; HH Kyu; E Gakidou; SI Hay; W Msemburi; MM Coates; MD Mooney; MS Fraser; A Sligar; HJ Larson; J Friedman; A Brown; L Dandona; N Fullman; J Haagsma; I Khalil; SS Lim; J Mikesell; AH Mokdad; M Moradi-Lakeh; K Pearson; B Silpakit; MJD Sorensen; AM Temesgen; SE Vollset; L Zoeckler; CJL Murray; R Alfonso-Cristancho; KM Harun; DM Prokop; EJ Mills; A Trickey; ON Ajala; T Bärnighausen; EL Ding; MS Farvid; AL Thorne-Lyman; S Won; JRA Fitchett; J Salomon; AA Abajobir; DG Hoy; NKM Alam; KH Abate; TT Ghiwot; AT Gebremedhin; KM Abbas; MM Abd El Razek; F Abd-Allah; AM Abdulle; SF Abera; YA Melaku; FH Tesfay; GY Abyu; TA Bayou; BD Betsu; AA Gebru; GB Hailu; T Tekle; AZ Yalew; HG Yebyo; I Abubakar; RW Aldridge; LJ Abu-Raddad; NME Abu-Rmeileh; AO Adebiyi; IA Adedeji; AL Adelekan; FA Ojelabi; K Adofo; AK Adou; TF Akinyemiju; DC Schwebel; JA Singh; N Akseer; FH Al Lami; Z Al-Aly; K Alam; RG Weintraub; PP Chiang; A Meretoja; AD Lopez; T Wijeratne; TR Driscoll; AH Kemp; J Leigh; AB Mekonnen; CK Karema; D Alasfoor; SFS Aldhahri; AS Terkawi; MA Alegretti; AV Aleman; ZA Alemu; C Cooper; A Deribew; PW Gething

Journal article

Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015

H Wang, TM Wolock, A Carter, G Nguyen, HH Kyu, E Gakidou, SI Hay, W Msemburi, MM Coates, MD Mooney, MS Fraser, A Sligar, HJ Larson, J Friedman, A Brown, L Dandona, N Fullman, J Haagsma, I Khalil, SS Lim Show all

Lancet HIV | ELSEVIER INC | Published : 2016

DOI: 10.1016/S2352-3018(16)30087-X

Download PDF

Abstract

Background Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015. Methods For countries without high-quality vital registration data, we estimated prevalence and incidence with data from antenatal care clinics and population-based seroprevalence surveys, and with assumptions by age and sex on initial CD4 distribution at infection, CD4 progression rates (probability of progression fro..

View full abstract

University of Melbourne Researchers

Robert Weintraub Author

Tissa Wijeratne Author

Melvin Marzan Author

Grants

Awarded by AXA Research Fund

Funding Acknowledgements

We thank the countless individuals who have contributed to the Global Burden of Disease (GBD) Study 2015 in various capacities. We specifically thank Jeffrey Eaton and John Stover. HW and CJLM received funding for this study from the Bill & Melinda Gates Foundation; the National Institute of Mental Health, National Institutes of Health (NIH; R01MH110163); and the National Institute on Aging, NIH (P30AG047845). LJAR acknowledges the support of Qatar National Research Fund (NPRP 04-924-3-251) who provided the main funding for generating the data provided to the GBD-Institute for Health Metrics and Evaluation effort. BPAQ acknowledges institutional support from PRONABEC (National Program of Scholarship and Educational Loan), provided by the Peruvian government. DB is supported by the Bill & Melinda Gates Foundation (grant number OPP1068048). JDN was supported in his contribution to this work by a Fellowship from Fundacao para a Ciencia e a Tecnologia, Portugal (SFRH/BPD/92934/2013). KD is supported by a Wellcome Trust Fellowship in Public Health and Tropical Medicine (grant number 099876). TF received financial support from the Swiss National Science Foundation (SNSF; project number P300P3-154634). AG acknowledges funding from Sistema Nacional de Investigadores de Panama-SNI. PJ is supported by Wellcome Trust-DBT India Alliance Clinical and Public Health Intermediate Fellowship. MK receives research support from the Academy of Finland, the Swedish Research Council, Alzheimerfonden, Alzheimer's Research & Prevention Foundation, Center for Innovative Medicine (CIMED) at Karolinska Institutet South Campus, AXA Research Fund, Wallenberg Clinical Scholars Award from the Knut och Alice Wallenbergs Foundation, and the Sheika Salama Bint Hamdan Al Nahyan Foundation. AK's work was supported by the Miguel Servet contract financed by the CP13/00150 and PI15/00862 projects, integrated into the National R&D&I and funded by the ISCIII (General Branch Evaluation and Promotion of Health Research), and the European Regional Development Fund (ERDF-FEDER). SML is funded by a National Institute for Health Research (NIHR) Clinician Scientist Fellowship (grant number NIHR/CS/010/014). HJL reports grants from the NIHR, EU Innovative Medicines Initiative, Centre for Strategic & International Studies, and WHO. WM is Program analyst, Population and Development, in the Peru Country Office of the United Nations Population Fund, which does not necessarily endorse this study. For UOM, funding from the German National Cohort Consortium (O1ER1511D) is gratefully acknowledged. KR reports grants from NIHR Oxford Biomedical Research Centre, NIHR Career Development Fellowship, and Oxford Martin School during the conduct of the study. GR acknowledges that work related to this paper has been done on the behalf of the GBD Genitourinary Disease Expert Group supported by the International Society of Nephrology (ISN). ISS reports grants from FAPESP (Brazilian public agency). RSS receives institutional support from Universidad de Ciencias Aplicadas y Ambientales, UDCA, Bogota Colombia. SS receives postdoctoral funding from the Fonds de la recherche en sante du Quebec (FRSQ), including its renewal. RTS was supported in part by grant number PROMETEOII/2015/021 from Generalitat Valenciana and the national grant PI14/00894 from ISCIII-FEDER. PY acknowledges support from Strategic Public Policy Research (HKU7003-SPPR-12).