Recent insights into humoral immunity targeting Plasmodium falciparum and Plasmodium vivax malaria
Michelle J Boyle, Linda Reiling, Faith H Osier, Freya JI Fowkes
INTERNATIONAL JOURNAL FOR PARASITOLOGY | ELSEVIER SCI LTD | Published : 2017
Recent efforts in malaria control have led to marked reductions in malaria incidence. However, new strategies are needed to sustain malaria elimination and eradication and achieve the World Health Organization goal of a malaria-free world. The development of highly effective vaccines would contribute to this goal and would be facilitated by a comprehensive understanding of humoral immune responses targeting Plasmodium falciparum and Plasmodium vivax malaria. New tools are required to facilitate the identification of vaccine candidates and the development of vaccines that induce functional and protective immunity. Here we discuss recent published findings, and unpublished work presented at th..View full abstract
Awarded by Wellcome Trust
Awarded by MRC
Awarded by Medical Research Council
This work is funded by the National Health and Medical Research Council, Australia (https://www.nhmrc.gov.au/) Early Career Fellowship (MJB), and the Australian Research Council (future fellowship to FJIF), Burnet Institute, Australia is supported by the National Health and Medical Research Council Australia Infrastructure for Research Institutes Support Scheme and by the Victorian State Government Operational Infrastructure Support, Australia. FHO is supported by the Wellcome Trust (089833) and an African Research Leader (ARL) Award that is jointly funded by the UK Medical Research Council (MRC) and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement, and is also part of the EDCTP2 program supported by the European Union. The funders had no role in preparation of the manuscript. This review is published with permission from the Director of the Kenyan Medical Research Institute (KEMRI).