Journal article

Early origins of mental disorder - risk factors in the perinatal and infant period

Louise Newman, Fiona Judd, Craig A Olsson, David Castle, Chad Bousman, Penelope Sheehan, Christos Pantelis, Jeffrey M Craig, Angela Komiti, Ian Everall

BMC PSYCHIATRY | BMC | Published : 2016

Abstract

BACKGROUND: There is increasing understanding of the significance of early neurodevelopment in establishing risk for the range of mental disorders. Models of the early aetiology of mental disorders are complex with a range of potential factors from genetic and epigenetic to environmental influencing neurological and psychological development. Whilst the mechanisms are not fully understood, this paper provides an overview of potential biological and neurobiological factors that might be involved. METHOD: An aetiological model is presented and discussed. The discussion includes a range of risk factors for mental disorder. Maternal anxiety disorder is presented and reviewed as an example of the..

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Grants

Awarded by ARC


Awarded by NHMRC


Awarded by Brain and Behaviour Research Foundation (NARSAD) Distinguished Investigator Award (US)


Awarded by NARSAD Young Investigator Grant


Awarded by Australian National Health and Medical Research Council


Awarded by Financial Markets Foundation for Children


Funding Acknowledgements

Professor Olsson is supported by an ARC Principal Research Fellowship (Discovery Outstanding Researcher Award, DP 1311459).Professor Pantelis was supported by a NHMRC Senior Principal Research Fellowship (628386, 1105825), and a Brain and Behaviour Research Foundation (NARSAD) Distinguished Investigator Award (US; Grant ID: 18722). Dr Chad Bousman was supported by a NARSAD Young Investigator Grant (Grant ID: 20526) and University of Melbourne Ronald Phillip Griffith Fellowship. Assoc. Professor Jeffrey M Craig is supported by the Australian National Health and Medical Research Council (Grant IDs: 1083779 and 1079102); the Financial Markets Foundation for Children (Grants IDs: 2014-134 and 2015-111) and the Victorian Government's Operational Infrastructure Support Program.