Journal article

Breast Milk Feeding, Brain Development, and Neurocognitive Outcomes: A 7-Year Longitudinal Study in Infants Born at Less Than 30 Weeks' Gestation

Mandy B Belfort, Peter J Anderson, Victoria A Nowak, Katherine J Lee, Charlotte Molesworth, Deanne K Thompson, Lex W Doyle, Terrie E Inder

The Journal of Pediatrics | MOSBY-ELSEVIER | Published : 2016


OBJECTIVES: To determine the associations of breast milk intake after birth with neurological outcomes at term equivalent and 7 years of age in very preterm infants STUDY DESIGN: We studied 180 infants born at <30 weeks' gestation or 50% of enteral intake as breast milk from 0-28 days of life. Outcomes included brain volumes measured by magnetic resonance imaging at term equivalent and 7 years of age, and cognitive (IQ, reading, mathematics, attention, working memory, language, visual perception) and motor testing at 7 years of age. We adjusted for age, sex, social risk, and neonatal illness in linear regression. RESULTS: A greater number of days on which infants received >50% breast milk wa..

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Awarded by Centre of Clinical Research Excellence

Awarded by Centre of Research Excellence in Newborn Medicine

Awarded by National Institutes of Health


Funding Acknowledgements

Funded by Australia's National Health & Medical Research Council; Centre of Clinical Research Excellence (546519 [to L.D. and P.A.]); Centre of Research Excellence in Newborn Medicine (1060733 [to L.D., P.A., and D.T.]); (237117 [to L.D.]); (491209 [to P. A.]); Senior Research Fellowship (1081288 [to P. A.]); Early Career Fellowships (1012236 [to D.T.] and 1053787 [to J.C.]); Career Development Fellowships (1085754 [to D.T.] and 1053609 [to K.L.]); National Institutes of Health (HD058056); United Cerebral Palsy Foundation (US); Leila Y. Mathers Charitable Foundation (US); the Brown Foundation (US); the Victorian Government's Operational Infrastructure Support Program; and The Royal Children's Hospital Foundation. V.N. was supported by the Cambridge Commonwealth Travelling Bursary (St John's College, Cambridge); Mary Euphrasia Mosley and Sir Bartle Frere Fund; Lord Mayor's 800th Anniversary Awards Trust; Nichol Young Foundation; and the Worts Travelling Scholars' Award. T.I. served on the Editorial Board of The Journal of Pediatrics (2007-2015). The other authors declare no conflicts of interest.