Mortality in mild cognitive impairment: A longitudinal study in memory clinics

MH Connors; D Ames; K Boundy; R Clarnette; S Kurrle; A Mander; J Ward; M Woodward; H Brodaty

Journal article

Mortality in mild cognitive impairment: A longitudinal study in memory clinics

MH Connors, D Ames, K Boundy, R Clarnette, S Kurrle, A Mander, J Ward, M Woodward, H Brodaty

Journal of Alzheimer S Disease | IOS PRESS | Published : 2016

DOI: 10.3233/JAD-160148

Abstract

Background: Patients with mild cognitive impairment (MCI) are at greater risk of mortality than the general population. Comparatively little research has examined predictors of mortality in MCI and no research has examined whether time-varying variables, such as change in cognition and function, predict survival. Objective: To identify predictors of mortality in patients with MCI. Methods: 185 patients with MCI were recruited from nine memory clinics around Australia. Patients completed measures of cognition, function, and neuropsychiatric symptoms over three years. Mortality data were obtained from state registries eight years after baseline. Results: 55 (30%) patients died within this peri..

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University of Melbourne Researchers

David Ames Author

Michael Woodward Author

Grants

Funding Acknowledgements

[ "The Dementia Collaborative Research Centre is funded by the National Health and Medical Research Council. We thank the staff at nine sites who collected data and the patients and caregivers who supported the study.", "Data collection was funded in part by Janssen-Cilag Pty Limited. Janssen-Cilag had no input into the design, execution, analysis, interpretation, or writing of this study." ]