Journal article

The impact of typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy on vision-related quality of life in Asian patients

Eva K Fenwick, Chui Ming Gemmy Cheung, Peng Guan Ong, Gavin Tan, Shu Yen Lee, Ian Yeo, Ching Yu Cheng, Tien Y Wong, Ecosse L Lamoureux

BRITISH JOURNAL OF OPHTHALMOLOGY | BMJ PUBLISHING GROUP | Published : 2017

Abstract

AIMS: To determine the impact of neovascular age-related macular degeneration (nAMD) on vision-related quality of life (VRQoL) in an Asian population. METHODS: In this cross-sectional study, 162 subjects with nAMD from the Asian AMD Phenotyping Study and 105 randomly sampled age-matched and gender-matched controls from the population-based Singapore Chinese Eye Study were recruited. nAMD was categorised as either polypoidal choroidal vasculopathy (PCV) or 'typical' AMD (tAMD). The reading, mobility and emotional well-being subscales of the impact of vision impairment (IVI) scale were validated using Rasch analysis and used as the main outcome measures and collectively referred to as VRQoL. M..

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Grants

Awarded by National Medical Research Council


Awarded by National Medical Research Council grant


Awarded by Singapore Bio Imaging Consortium


Awarded by Biomedical Research Council


Awarded by National Health and Medical Research Council (NHMRC)


Funding Acknowledgements

This study was supported by grants from the National Medical Research Council (STaR/0003/2008 and NIG/1003/2009), National Medical Research Council grant NMRC/NIG/1003/2009; the Singapore Bio Imaging Consortium (C-011/2006) and the Biomedical Research Council (08/1/35/19/550). EF is funded by a National Health and Medical Research Council (NHMRC) Early Career Fellowship (# 1072987). The Centre for Eye Research Australia receives Operational Infrastructure Support from the Victorian Government.