Journal article
Symptoms and patient factors associated with longer time to diagnosis for colorectal cancer: Results from a prospective cohort study
FM Walter, JD Emery, S Mendonca, N Hall, HC Morris, K Mills, C Dobson, C Bankhead, M Johnson, GA Abel, MD Rutter, W Hamilton, GP Rubin
British Journal of Cancer | SPRINGERNATURE | Published : 2016
DOI: 10.1038/bjc.2016.221
Abstract
Background:The objective of this study is to investigate symptoms, clinical factors and socio-demographic factors associated with colorectal cancer (CRC) diagnosis and time to diagnosis.Methods:Prospective cohort study of participants referred for suspicion of CRC in two English regions. Data were collected using a patient questionnaire, primary care and hospital records. Descriptive and regression analyses examined associations between symptoms and patient factors with total diagnostic interval (TDI), patient interval (PI), health system interval (HSI) and stage.Results:A total of 2677 (22%) participants responded; after exclusions, 2507 remained. Participants were diagnosed with CRC (6.1%,..
View full abstractGrants
Awarded by National Institute for Health Research (NIHR) Programme Grants for Applied Research programme
Awarded by National Institutes of Health Research (NIHR)
Funding Acknowledgements
We thank all the patients who contributed to this study and the public representatives in the study team for their valuable contributions to the project: Sue Ballard, Victor Boulter and Margaret Johnson. We thank the clinical teams, research nurses and clinic administrators at the participating hospitals: Cambridge University Hospitals NHS Foundation Trust - Mr Miller, Dr Cameron, Kathy Restarick and Debbie Hugh; North Tees & Hartlepool NHS Foundation Trust - Dr Rutter, Sue Kelsey and Debbie Whetter; County Durham and Darlington NHS Foundation Trust - Dr Cundell, Jill Deane and Gill Horner. Finally, we acknowledge the contribution to the research presented in this paper made by members of the Discovery Programme Steering Committee: Roger Jones (chair), Jon Banks, Alison Clutterbuck, Ardiana Gjini, Joanne Hartland, Maire Justice, Jenny Knowles, Richard Neal and Peter Rose. This study presents independent research funded by the National Institute for Health Research (NIHR) Programme Grants for Applied Research programme (RP-PG-0608-10045). The views expressed are those of the authors and not necessarily those of the National Health Service, the National Institute for Health Research or the Department of Health.