Down-regulation of phosphatidylinositol 3 '-kinase/AKT/molecular target of rapamycin metabolic pathway by primary letrozole-based therapy in human breast cancer

Daniele Generali, Stephen B Fox, Maria Pia Brizzi, Giovanni Allevi, Simone Bonardi, Sergio Aguggini, Manuela Milani, Alessandra Bersiga, Leticia Campo, Rossana Dionisio, Federica Vergoni, Roberto Giardini, Luigi Dog Liotti, Alberto Bottini, Adrian L Harris, Alfredo Berruti