Journal article
New advances in CMV and immunosenescence
P Sansoni, R Vescovini, FF Fagnoni, A Akbar, R Arens, YL Chiu, L Čičin-Šain, J Dechanet-Merville, E Derhovanessian, S Ferrando-Martinez, C Franceschi, D Frasca, T Fulöp, D Furman, E Gkrania-Klotsas, F Goodrum, B Grubeck-Loebenstein, M Hurme, F Kern, D Lilleri Show all
Experimental Gerontology | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2014
Open access
Abstract
Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines. An increasing number of immunological, clinical and epidemiological studies suggest that persistent Cytomegalovirus (CMV) infection is associated with accelerated aging of the immune system and with several age-related diseases. However, current evidence on whether and how human CMV (HCMV) infection is implicated in immunosenescence and in age-related diseases remains incomplete and many aspects of CMV involvement in immune aging remain controversial. The attendees of the 4th International Workshop on "CMV & I..
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Funding Acknowledgements
The Workshop was partially supported by the University of Parma, Fondazione CARIPARMA and Regione Emilia-Romagna (Programma di Ricerca Regione/Universita-AREA1. Strategic programme: "A TAILORED APPROACH TO THE IMMUNE-MONITORING AND CLINICAL MANAGEMENT OF VIRAL AND AUTOIMMUNE DIESEASE").