Journal article
Associations between muscle strength, spirometric pulmonary function and mobility in healthy older adults
E Sillanpää, L Stenroth, AY Bijlsma, T Rantanen, JS McPhee, TM Maden-Wilkinson, DA Jones, MV Narici, H Gapeyeva, M Pääsuke, Y Barnouin, JY Hogrel, GS Butler-Browne, CGM Meskers, AB Maier, T Törmäkangas, S Sipilä
Age | SPRINGER | Published : 2014
Abstract
Pathological obstruction in lungs leads to severe decreases in muscle strength and mobility in patients suffering from chronic obstructive pulmonary disease. The purpose of this study was to investigate the interdependency between muscle strength, spirometric pulmonary functions and mobility outcomes in healthy older men and women, where skeletal muscle and pulmonary function decline without interference of overt disease. A total of 135 69- to 81-year-old participants were recruited into the cross-sectional study, which was performed as a part of European study MyoAge. Full, partial and no mediation models were constructed to assess the interdependency between muscle strength (handgrip stren..
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Awarded by Association Française contre les Myopathies
Funding Acknowledgements
This study was supported by an unrestricted grant from the seventh framework program MyoAge (HEALTH-2007-2.4.5-10), 050-060-810 Netherlands Consortium for Healthy Aging (NCHA)), Estonian Science Foundation (grants # 8736 and # 7823), the Estonian Ministry of Education and Research (grant SF01080114As08) and the Association Francaise Contre les Myopathies (AFM).