Journal article

Gait in children and adolescents with Charcot-Marie-Tooth disease: a systematic review

Rachel A Kennedy, Kate Carroll, Jennifer L McGinley

Journal of the Peripheral Nervous System | WILEY-BLACKWELL | Published : 2016

Abstract

Symptoms of Charcot-Marie-Tooth (CMT) disease typically arise in childhood or adolescence with gait difficulty most common. A systematic review was conducted to synthesise, review, and characterise gait in paediatric CMT. Health-related electronic databases were reviewed with search terms related to CMT and gait. Of 454 articles, 10 articles describing seven studies met eligibility criteria; samples ranged from 1 to 81, included mixed CMT sub-types and had a participant mean age of 13 years. Assessments included a variety of methods to examine only barefoot gait. Heterogeneity of gait patterns was noted. Children and adolescents with CMT walked slower, most likely due to shorter stride lengt..

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University of Melbourne Researchers