Journal article

Specific oral tolerance induction in childhood

Rachel L Peters, Thanh D Dang, Katrina J Allen

PEDIATRIC ALLERGY AND IMMUNOLOGY | WILEY | Published : 2016

Abstract

Food allergy continues to be a significant public health concern for which there are no approved treatments and management strategies primarily include allergen avoidance and pharmacological measures for accidental exposures. Food allergy is thought to result from either a failure to establish oral tolerance or the breakdown of existing oral tolerance, and therefore, experimental preventative and treatment strategies are now aimed at inducing specific oral tolerance. This may occur in infancy prior to the development of food allergy through the optimal timing of dietary exposure (primary oral tolerance induction) or as a treatment for established food allergy through oral immunotherapy (seco..

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