Journal article
Effects of longitudinal body mass index variability on microvasculature over 5 years in adult Chinese
W Gong, Y Hu, Y Niu, D Wang, Y Wang, Y Li, BA Holden, M He
Obesity | WILEY | Published : 2016
DOI: 10.1002/oby.21398
Abstract
Objective To explore the associations of 5-year trend and fluctuation in body mass index (BMI) with retinal vascular caliber in a middle-aged and elderly Chinese population. Methods Participants age ≥40 years were recruited in a prospective study. Baseline BMI data were collected in 2008, and the participants were re-examined annually until 2012. Retinal vascular caliber was measured from fundus photographs collected in 2012. BMI trend was calculated as the slope of BMI against the time of examinations. BMI fluctuation was defined as the root mean square error around the regression line of BMI over time (BMI RMSE) and the coefficient of variation of BMI (BMI CV). Results Rising BMI trend was..
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Awarded by National Natural Science Foundation of China
Funding Acknowledgements
The. study was supported by the Fundamental Research Funds of the State Key Laboratory in Ophthalmology, the National Natural Science Foundation of China (81125007), and a research grant from the Brien Holden Vision Institute. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.