Shared genetic determinants of axial length and height in children: The Guangzhou twin eye study

Abstract

Objectives: To describe the association between axial length (AL) and height and to estimate the extent to which shared genetic or environmental factors influence this covariance. Methods: Study participants were recruited from the Guangzhou Twin Registry. Axial length was measured using partial coherence laser interferometry. Height was measured with the participants standing without shoes. We computed twin pairwise correlations and cross-twin cross-trait correlations between AL and height for monozygotic and dizygotic twins and performed model-fitting analyses using a multivariate Cholesky model. The right eye was arbitrarily selected to represent AL of participants. Results: Five hundred ..