Quantitative analysis of anterior segment optical coherence tomography images: The zhongshan angle assessment program

Abstract

Aim: To describe a new image analysis method and software for anterior chamber images obtained by the anterior-segment optical coherence tomography (AS-OCT) and to assess its intraobserver and interobserver measurement reproducibility. Methods: Twenty 8-bit greyscale 600×300 AS-OCT images with apparent wide angles and 20 images with apparent narrow angles were consecutively selected from a database. Two glaucoma fellowship-trained ophthalmologists used proprietary image analysis software to analyse the images twice. Algorithms defined the borders and curvatures of anterior chamber (AC) structures and measured AC parameters using scleral spur location as the only observer input. The intraobse..