Journal article

Genetic influences on the difference in variability of height, weight and body mass index between Caucasian and East Asian adolescent twins

Y-M Hur, J Kaprio, WG Iacono, DI Boomsma, M McGgue, K Silventoinen, NG Martin, M Luciano, PM Visscher, RJ Rose, M He, J Ando, S Ooki, K Nonaka, CCH Lin, HR Lajunen, BK Cornes, M Bartels, CEM van Beijsterveldt, SS Cherny Show all

INTERNATIONAL JOURNAL OF OBESITY | NATURE PUBLISHING GROUP | Published : 2008

Abstract

OBJECTIVE: Twin studies are useful for investigating the causes of trait variation between as well as within a population. The goals of the present study were two-fold: First, we aimed to compare the total phenotypic, genetic and environmental variances of height, weight and BMI between Caucasians and East Asians using twins. Secondly, we intended to estimate the extent to which genetic and environmental factors contribute to differences in variability of height, weight and BMI between Caucasians and East Asians. DESIGN: Height and weight data from 3735 Caucasian and 1584 East Asian twin pairs (age: 13-15 years) from Australia, China, Finland, Japan, the Netherlands, South Korea, Taiwan and ..

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University of Melbourne Researchers

Grants

Awarded by National Institute of Alcohol Abuse and Alcoholism


Awarded by Academy of Finland


Awarded by US National Institute of Health


Awarded by Australian twin data collection


Awarded by National Natural Science Foundation of China


Awarded by New Century Excellent Talents in University, National Ministry of Education


Awarded by Guangzhou Science and Technology Development Fund


Awarded by NIMH


Awarded by NIH



Awarded by NATIONAL EYE INSTITUTE


Awarded by NATIONAL INSTITUTE OF MENTAL HEALTH


Awarded by NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM


Awarded by NATIONAL INSTITUTE ON DRUG ABUSE


Funding Acknowledgements

The South Korean Twin Registry has been supported by the Pioneer Fund, New York. The Finnish Twin Study is a part of the Academy of Finland Centre of Excellence in Complex Disease Genetics. The Finnish Twin Studies have been supported by the National Institute of Alcohol Abuse and Alcoholism (Grants AA-12502, AA-00145 and AA-09203 to RJR) and the Academy of Finland (Grants 100499, and 205585 to JK). The Minnesota Twin Family Study has been supported by the US National Institute of Health Grants, DA13240, DA05147 and AA09367. The Netherlands Twin Registry has been supported by NWO/SPI 56-464-14192, NWO 480-04-004, NWO/VENI 451-04-034 and NWO/Bilateral Agreement 463-06-001. Australian twin data collection was funded by ARC Grants (A79600334, A79906588, A79801419, DP0212016, DP0343921). The Guangzhou Twin Eye Studies have been supported by National Natural Science Foundation of China 30772393, Program for New Century Excellent Talents in University, National Ministry of Education NCET06-0720, and Guangzhou Science and Technology Development Fund 2006Z3-E0061. Funding resource for the Japanese Twin Studies are Brain Science and Education Program (II), RISTEX, JST. In addition, we acknowledge NIMH Grant MH20030 awarded to Karen Mitchell (PI: Michael Neale) and NIH Grant EY-12562 awarded to Stacey Cherny.