Journal article

Human TRAV1-2-negative MR1-restricted T cells detect S-pyogenes and alternatives to MAIT riboflavin-based antigens

Erin W Meermeier, Bruno F Laugel, Andrew K Sewell, Alexandra J Corbett, Jamie Rossjohn, James McCluskey, Melanie J Harriff, Tamera Franks, Marielle C Gold, David M Lewinsohn

NATURE COMMUNICATIONS | NATURE PUBLISHING GROUP | Published : 2016

Grants

Awarded by United States Department of Veterans Affairs Biomedical Laboratory Research


Awarded by U.S. Department of Veterans Affairs Clinical Sciences Research and Development Program


Awarded by NIH


Funding Acknowledgements

We thank Ted Hansen for his generous gift of the alpha-MR1 antibody (26.5), Branch Moody for his generous gift of the alpha-CD1 antibodies, Deborah Lewinsohn, Nicholas Meermeier and Eisa Mahyari for critical reading of the manuscript and Miranda Gilchrist for her FACS expertise. This work was supported by Merit Review Awards #I01 BX001231 (M.C.G.); I01 BX000533 (D.M.L.) from the United States Department of Veterans Affairs Biomedical Laboratory Research and Career Development Award IK2 CX000538 from the U.S. Department of Veterans Affairs Clinical Sciences Research and Development Program (M.C.H.) and resources and the use of facilities at the VA Portland Health Care System; NIH AI078965 (M.C.G.); AI048090, AI048090-15 (D.M.L.); AI078903-05 (E.W.M.); HL83808-05 (E.W.M.); and AI007472-21 (E.W.M.). Disclaimer The contents of this manuscript do not represent the views of the U.S. Department of Veterans Affairs or the United States Government.