Journal article

Human ribosomes from cells with reduced dyskerin levels are intrinsically altered in translation

Marianna Penzo, Laura Rocchi, Sabine Brugiere, Domenica Carnicelli, Carmine Onofrillo, Yohann Coute, Maurizio Brigotti, Lorenzo Montanaro

The FASEB Journal | FEDERATION AMER SOC EXP BIOL | Published : 2015

Grants

Awarded by Association for International Cancer Research


Awarded by Associazione Italiana per la Ricerca sul Cancro


Awarded by Italian Ministry of Education, University and National Research Project


Awarded by PRIME-XS project


Awarded by Worldwide Cancer Research


Funding Acknowledgements

The authors are in debt to Drs. D. Ruggero, B. Mazumder and J.-J. Diaz for providing reagents, and to Drs. O. Gandrillon, S. Giraud, A. T. Thu Lefebvre, and L. Grossier (Centre de Genetique et de Physiologie Moleculaire et Cellulaire, Lyon, France) for help in the preliminary part of the study and for discussion. The authors thank the Center for Applied Biomedical Research of S. Orsola-Malpighi University Hospital in Bologna for making available several instruments. This work has been supported by grants from the Association for International Cancer Research (09-0083), Associazione Italiana per la Ricerca sul Cancro (IG-11416), the Italian Ministry of Education, University and National Research Project (Grant 20104AE23N_002), the PRIME-XS project (Grant 262067), funded by the European Union 7th Framework Programme (awarded to L.M.), and Funds from the Pallotti Legacy for research on cancer (to L.M. and M.B.). The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org) via the PRIDE partner repository (31) with the data set identifier PXD001274.