Journal article

BACTERIAL-COLONIZATION OF THE NASOPHARYNX PREDICTS VERY EARLY-ONSET AND PERSISTENCE OF OTITIS-MEDIA IN AUSTRALIAN ABORIGINAL INFANTS

AJ LEACH, JB BOSWELL, V ASCHE, TG NIENHUYS, JD MATHEWS

PEDIATRIC INFECTIOUS DISEASE JOURNAL | LIPPINCOTT WILLIAMS & WILKINS | Published : 1994

Abstract

Otitis media (OM) develops in the first months of life and persists throughout childhood in many rural Aboriginal children. We have followed Aboriginal and non-Aboriginal infants from birth to determine the relationship of the early onset of OM to nasopharyngeal colonization with respiratory pathogens. Aboriginal infants were colonized with multiple species of respiratory bacteria (Moraxella catarrhalis, Haemophilus influenzae, Streptococcus pneumoniae) at a rate of 5% per day and the timing of colonization predicted the onset of persistent OM in individual Aboriginal infants. Non-Aboriginal infants became colonized by M. catarrhalis alone at the slower rate of 1% per day and experienced tra..

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