The Effect of Round Window Sealants on Delayed Hearing Loss in a Guinea Pig Model of Cochlear Implantation

Abstract

Aim: To determine whether the type of material used to seal the cochlea after round window cochlear implantation influences delayed hearing loss. Background: Cochlear implants are now prescribed to patients with residual, low-frequency hearing. This hearing - which provides perceptual benefits for the implanted ear - is frequently lost for unknown reasons weeks to months after surgery in a proportion of patients. A post-surgical change in cochlear mechanics, related to the material used to seal the cochlea after round window implantation, may contribute to this loss. Methods: An electrode array was implanted in Guinea pigs via the round window, which was then sealed with muscle, periosteum, ..