The Effect of Round Window Sealants on Delayed Hearing Loss in a Guinea Pig Model of Cochlear Implantation
David Rowe, Scott Chambers, Amy Hampson, Hayden Eastwood, Stephen O'Leary
OTOLOGY & NEUROTOLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2016
AIM: To determine whether the type of material used to seal the cochlea after round window cochlear implantation influences delayed hearing loss. BACKGROUND: Cochlear implants are now prescribed to patients with residual, low-frequency hearing. This hearing-which provides perceptual benefits for the implanted ear-is frequently lost for unknown reasons weeks to months after surgery in a proportion of patients. A post-surgical change in cochlear mechanics, related to the material used to seal the cochlea after round window implantation, may contribute to this loss. METHODS: An electrode array was implanted in guinea pigs via the round window, which was then sealed with muscle, periosteum, or f..View full abstract
This work was funded by the Garnett Passe and Rodney Williams Memorial Foundation.