Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis
Mary Speir, Kate E Lawlor, Stefan P Glaser, Gilu Abraham, Seong Chow, Adam Vogrin, Keith E Schulze, Ralf Schuelein, Lorraine A O'Reilly, Kylie Mason, Elizabeth L Hartland, Trevor Lithgow, Andreas Strasser, Guillaume Lessene, David CS Huang, James E Vince, Thomas Naderer
Nature Microbiology | NATURE PUBLISHING GROUP | Published : 2016
Awarded by NHMRC (Canberra, Australia)
Awarded by CDF1 fellowships
Awarded by Independent Research Institutes Infrastructure Support Scheme grant
Awarded by Leukemia and Lymphoma Society (SCOR)
The authors thank members of the Monash Micro Imaging facility for their technical support, D. Newman (Monash University) for the statistical analysis, E. Latz (University of Bonn) for immortalized C57Bl/6 macrophages and D. Vaux, J. Silke, W. Alexander, S. Masters, L. Lindqvist and P. Bouillet (Walter and Eliza Hall Institute of Medical Research) for providing mice or reagents. This study was funded by grants and fellowships from the NHMRC (Canberra, Australia), programme grants 606788 (T.L. and E.L.H.) and 1016701 (A. S.), project grants 1024839 (T.N. and J.E.V.), 1051235 (S.P.G.) and 1009145 (L.O.R.), CDF1 fellowships 1052598 (J.E.V.) and 1020363 (A. S.), an NHMRC infrastructure grant, Independent Research Institutes Infrastructure Support Scheme grant 361646, the Victorian State Government (OIS grant) and the Leukemia and Lymphoma Society (SCOR grants 7413 and 7001-13).