Associations between outdoor fungal spores and childhood and adolescent asthma hospitalizations

R Tham; D Vicendese; SC Dharmage; RJ Hyndman; E Newbigin; E Lewis; M O'Sullivan; AJ Lowe; P Taylor; P Bardin; MLK Tang; MJ Abramson; B Erbas

Journal article

Associations between outdoor fungal spores and childhood and adolescent asthma hospitalizations

R Tham, D Vicendese, SC Dharmage, RJ Hyndman, E Newbigin, E Lewis, M O'Sullivan, AJ Lowe, P Taylor, P Bardin, MLK Tang, MJ Abramson, B Erbas

Journal of Allergy and Clinical Immunology | MOSBY-ELSEVIER | Published : 2017

DOI: 10.1016/j.jaci.2016.06.046

Abstract

Background Childhood asthma is a significant public health problem and severe exacerbations can result in diminished quality of life and hospitalization. Objective We sought to examine the contribution of outdoor fungi to childhood and adolescent asthma hospitalizations. Methods The Melbourne Air Pollen Children and Adolescent study is a case-crossover study of 644 children and adolescents (aged 2-17 years) hospitalized for asthma. The Melbourne Air Pollen Children and Adolescent study collected individual data on human rhinovirus infection and sensitization to Alternaria and Cladosporium and daily counts of ambient concentrations of fungal spores, pollen, and air pollutants. Conditional log..

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University of Melbourne Researchers

Rachel Tham Author

Don Vicendese Author

Shyamali Dharmage Author

Ed Newbigin Author

Related Projects (1)

THE IMPACT OF OUTDOOR AUTOALLERGEN EXPOSURE ON ASTHMA EXACERBATIONS IN CHILDREN AND ADOLESCENTS

Asthma is a chronic condition usually diagnosed in childhood and an important public health concern. We do not fully understand what trigger..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The Melbourne Air Pollen Children and Adolescent Health study was funded by the National Health and Medical Research Council (NHMRC) Project ID: 541934, but the NHMRC had no part in the study design, collection, analysis, or interpretation of the data, the writing of this manuscript, or the decision to submit it for publication. R.T. is funded by an NHMRC PhD Postgraduate Scholarship and a Centre for Air quality & health Research and evaluation (NHMRC Centre of Research Excellence) top-up scholarship. S.C.D. and A.J.L. are funded by the NHMRC.