Associations between outdoor fungal spores and childhood and adolescent asthma hospitalizations
Rachel Tham, Don Vicendese, Shyamali C Dharmage, Rob J Hyndman, Ed Newbigin, Emma Lewis, Molly O'Sullivan, Adrian J Lowe, Philip Taylor, Philip Bardin, Mimi LK Tang, Michael J Abramson, Bircan Erbas
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | MOSBY-ELSEVIER | Published : 2017
BACKGROUND: Childhood asthma is a significant public health problem and severe exacerbations can result in diminished quality of life and hospitalization. OBJECTIVE: We sought to examine the contribution of outdoor fungi to childhood and adolescent asthma hospitalizations. METHODS: The Melbourne Air Pollen Children and Adolescent study is a case-crossover study of 644 children and adolescents (aged 2-17 years) hospitalized for asthma. The Melbourne Air Pollen Children and Adolescent study collected individual data on human rhinovirus infection and sensitization to Alternaria and Cladosporium and daily counts of ambient concentrations of fungal spores, pollen, and air pollutants. Conditional ..View full abstract
Awarded by National Health and Medical Research Council (NHMRC)
The Melbourne Air Pollen Children and Adolescent Health study was funded by the National Health and Medical Research Council (NHMRC) Project ID: 541934, but the NHMRC had no part in the study design, collection, analysis, or interpretation of the data, the writing of this manuscript, or the decision to submit it for publication. R.T. is funded by an NHMRC PhD Postgraduate Scholarship and a Centre for Air quality & health Research and evaluation (NHMRC Centre of Research Excellence) top-up scholarship. S.C.D. and A.J.L. are funded by the NHMRC.