Granulocyte macrophage colony-stimulating factor induces CCL17 pro uction via IRF4 to mediate inflammation

Adrian Achuthan; Andrew D Cook; Ming-Chin Lee; Reem Saleh; Hsu-Wei Khiew; Melody WN Chang; Cynthia Louis; Andrew J Fleetwood; Derek C Lacey; Anne D Christensen; Ashlee T Frye; Pui Yeng Lam; Hitoshi Kusano; Koji Nomura; Nancy Steiner; Irmgard Foerster; Stephen L Nutt; Moshe Olshansky; Stephen J Turner; John A Hamilton

Journal article

Granulocyte macrophage colony-stimulating factor induces CCL17 pro uction via IRF4 to mediate inflammation

Adrian Achuthan, Andrew D Cook, Ming-Chin Lee, Reem Saleh, Hsu-Wei Khiew, Melody WN Chang, Cynthia Louis, Andrew J Fleetwood, Derek C Lacey, Anne D Christensen, Ashlee T Frye, Pui Yeng Lam, Hitoshi Kusano, Koji Nomura, Nancy Steiner, Irmgard Foerster, Stephen L Nutt, Moshe Olshansky, Stephen J Turner, John A Hamilton

JOURNAL OF CLINICAL INVESTIGATION | AMER SOC CLINICAL INVESTIGATION INC | Published : 2016

DOI: 10.1172/JCI87828

University of Melbourne Researchers

Stephen Nutt Author Medical Biology (W.E.H.I.)

Andrew Fleetwood Author Medicine - Royal Melbourne Hospital

John Hamilton Author Medicine - Royal Melbourne Hospital

Kevin Lee Author Medicine - Royal Melbourne Hospital

Derek Lacey Author Medicine - Royal Melbourne Hospital

Related Projects (2)

Cytokine Regulation Of Inflammatory Pain

What drives the pain associated with inflammation is unknown as is the relationship between pain and the extent of tissue damage associated ..

Molecular Control Of Virus-Specific T Cell Responses

Upon virus infection, a subset of white blood cells, called killer T cells, are recruited to fight the infection. This proposal aims to exam..

Grants

Awarded by Deutsche Forschungsgemeinschaft (DFG)

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

AA and JAH were supported in part by a grant from GSK. AD Cook and JAH were supported by a grant (1043147) and JAH by a Senior Principal Research Fellowship from the National Health and Medical Research Council of Australia. AD Christensen was supported by a postdoc fellowship from Novo Nordisk A/S, Denmark. NS and IF were supported by the Deutsche Forschungsgemeinschaft (DFG) through SFB704. IF is a member of the DFG-funded cluster of excellence ImmunoSensation. SLN was supported by grants (361646, 575500 and 1054925) from the National Health and Medical Research Council of Australia. SJT was supported by grants (5671222 and 1003131) from the National Health and Medical Research Council of Australia and by an Australian Research Council Future Fellowship.