Journal article
The effects of stress-tension on depression and anxiety symptoms: Evidence from a novel twin modelling analysis
CG Davey, C López-Solà, M Bui, JL Hopper, C Pantelis, LF Fontenelle, BJ Harrison
Psychological Medicine | CAMBRIDGE UNIV PRESS | Published : 2016
Abstract
Background Negative mood states are composed of symptoms of depression and anxiety, and by a third factor related to stress, tension and irritability. We sought to clarify the nature of the relationships between the factors by studying twin pairs. Method A total of 503 monozygotic twin pairs completed the Depression Anxiety Stress Scales (DASS), an instrument that assesses symptoms of depression, anxiety and stress-tension. We applied a recently developed twin regression methodology - Inference about Causation from Examination of FAmiliaL CONfounding (ICE FALCON) - to test for evidence consistent with the existence of 'causal' influences between the DASS factors. Results There was evidence c..
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Funding Acknowledgements
The study was funded by an Early Career Researcher Grant to B.J.H. from The University of Melbourne. C.G.D. is supported by a National Health and Medical Research Council of Australia (NHMRC) Clinical Career Development Fellowship. C.L.-S. is supported by the Spanish Ministry of Education, Culture and Sport. J.L.H. is supported by a NHMRC Senior Principal Research Fellowship, and as a Distinguished Visiting Professor at Seoul National University, Korea. C.P. is supported by a NHMRC Senior Principal Research Fellowship, and a Brain and Behavior Research Foundation (NARSAD) Distinguished Investigator Award. B.J.H. is supported by an NHMRC Clinical Career Development Fellowship. This research was facilitated through access to the ATR, a national resource supported by an Enabling Grant from the NHMRC.