Journal article

Sonochemical and sustainable synthesis of graphene-gold (G-Au) nanocomposites for enzymeless and selective electrochemical detection of nitric oxide

Renu Geetha Bai, Kasturi Muthoosamy, Meifang Zhou, Muthupandian Ashokkumar, Nay Ming Huang, Sivakumar Manickam



In this study, a sonochemical approach was utilised for the development of graphene-gold (G-Au) nanocomposite. Through the sonochemical method, simultaneous exfoliation of graphite and the reduction of gold chloride occurs to produce highly crystalline G-Au nanocomposite. The in situ growth of gold nanoparticles (AuNPs) took place on the surface of exfoliated few-layer graphene sheets. The G-Au nanocomposite was characterised by UV-vis, XRD, FTIR, TEM, XPS and Raman spectroscopy techniques. This G-Au nanocomposite was used to modify glassy carbon electrode (GCE) to fabricate an electrochemical sensor for the selective detection of nitric oxide (NO), a critical cancer biomarker. G-Au modified..

View full abstract

University of Melbourne Researchers


Awarded by Ministry of Higher Education (MOHE), Malaysia

Funding Acknowledgements

The authors would like to thank Ministry of Higher Education (MOHE), Malaysia for the FRGS research Grant (F0018.5402). The authors would like to thank Dr Alagarsamy Pandikumar, Mr Perumal Rameshkumar and Mr Mehmood Shahid (Low Dimensional Materials Research Centre, Department of Physics, University of Malaya, Malaysia) for their assistance in electrochemical experiments.