Journal article
Postoperative seizure control in patients with tumor-associated epilepsy
A Neal, A Morokoff, TJ O'Brien, P Kwan
Epilepsia | WILEY | Published : 2016
DOI: 10.1111/epi.13562
Abstract
Objective: The patterns of postoperative seizure control and response to antiepileptic drugs (AEDs) in tumor-associated epilepsy (TAE) are poorly understood. We aim to document these characteristics in patients with supratentorial gliomas. Methods: This was a retrospective analysis of 186 patients with supratentorial gliomas. Seizure patterns were classified into four groups: A, no postoperative seizure; B, early postoperative seizure control within 6 months; C, fluctuating seizure control; and D, never seizure-free. Rates and duration of seizure freedom, subsequent seizure relapse, and response to AED were analyzed. Results: Among patients included, 49 (26.3%) had grade II, 28 (15.1%) had g..
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Funding Acknowledgements
Dr. Andrew Neal was supported by an Australian Postgraduate Award Scholarship (University of Melbourne), Epilepsy Society Australia UCB Clinical Pharma Scholarship and by the Royal Melbourne Hospital Neuroscience Foundation. Andrew Neal conducted statistical analysis with the assistance of Mark Tacey from Centre for Clinical Epidemiology, Biostatistics and Health Services Research, Royal Melbourne Hospital, University of Melbourne, Vic. 3050.