Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation

Vidhi Gaur; Timothy Connor; Andrew Sanigorski; Sheree D Martin; Clinton R Bruce; Darren C Henstridge; Simon T Bond; Kevin A McEwen; Lyndal Kerr-Bayles; Trent D Ashton; Cassandra Fleming; Min Wu; Lisa S Pike Winer; Denise Chen; Gregg M Hudson; John WR Schwabe; Keith Baar; Mark A Febbraio; Paul Gregorevic; Frederick M Pfeffer; Ken R Walder; Mark Hargreaves; Sean L McGee

Journal article

Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation

Vidhi Gaur, Timothy Connor, Andrew Sanigorski, Sheree D Martin, Clinton R Bruce, Darren C Henstridge, Simon T Bond, Kevin A McEwen, Lyndal Kerr-Bayles, Trent D Ashton, Cassandra Fleming, Min Wu, Lisa S Pike Winer, Denise Chen, Gregg M Hudson, John WR Schwabe, Keith Baar, Mark A Febbraio, Paul Gregorevic, Frederick M Pfeffer Show all

Cell Reports | CELL PRESS | Published : 2016

DOI: 10.1016/j.celrep.2016.08.005

University of Melbourne Researchers

Mark Hargreaves Author

Paul Gregorevic Author Physiology

simon Bond Author Baker Department of Cardiometabolic Health

Grants

Awarded by National Health and Medical Research Council (NHMRC) of Australia

Awarded by Wellcome Trust

Funding Acknowledgements

The authors wish to thank Assoc. Prof. Peter Meikle (Metabolomics Laboratory, Baker IDI) for assistance with lipid analysis, Hongwei Qian for AAV production, and Alex Nelson for technical assistance. This research was supported by the Diabetes Australia Research Trust Viertel Award and by grants from the National Health and Medical Research Council (NHMRC) of Australia (1027727) and the Deakin University Molecular and Medical Research Strategic Research Centre to S.L.M. J.W.R.S. is supported by Wellcome Trust Senior Investigator Award WT100237 and is a Royal Society Merit Award Holder. M.A.F., P.G., and S.L.M. are supported by research fellowships from the NHMRC.