Journal article

Selective Targeting of Cyclin E1-Amplified High-Grade Serous Ovarian Cancer by Cyclin-Dependent Kinase 2 and AKT Inhibition

George Au-Yeung, Franziska Lang, Walid J Azar, Chris Mitchell, Kate E Jarman, Kurt Lackovic, Diar Aziz, Carleen Cullinane, Richard B Pearson, Linda Mileshkin, Danny Rischin, Alison M Karst, Ronny Drapkin, Dariush Etemadmoghadam, David DL Bowtell

Clinical Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2017

Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by NHMRC


Awarded by Pfizer Cancer Research Grant


Awarded by U. S. Army Medical Research and Materiel Command


Awarded by National Cancer Institute at the NIH


Awarded by National Health and Medical Research Council of Australia (NHMRC)


Funding Acknowledgements

This work was supported by a National Health and Medical Research Council (NHMRC) program grant (APP1092856; to D. D. L. Bowtell), NHMRC project grant (APP1042358; to D. Etemadmoghadam), a Pfizer Cancer Research Grant (WI80176; to G. Au-Yeung), University of Melbourne Australian Postgraduate Award (to G. Au-Yeung), the U. S. Army Medical Research and Materiel Command (OC140511; to D. D. L. Bowtell and R. Drapkin), the National Cancer Institute at the NIH (P50-CA083636 and R21 CA156021; to R. Drapkin); the Honorable Tina Brozman 'Tina's Wish' Foundation (to R. Drapkin), the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (to R. Drapkin), a Canadian Institutes of Health Research Fellowship (to A. M. Karst), a Kaleidoscope of Hope Foundation Young Investigator Research grant (to A. M. Karst), the Basser Center for BRCA, and Department of Obstetrics and Gynecology at the University of Pennsylvania Perelman School of Medicine (to R. Drapkin). The Australian Ovarian Cancer Study is supported by the Peter MacCallum Cancer Centre Foundation, U. S. Army Medical Research and Materiel Command under DAMD17-01-1-0729, The Cancer Council Victoria, Queensland Cancer Fund, The Cancer Council New South Wales, The Cancer Council South Australia, The Cancer Foundation of Western Australia, The Cancer Council Tasmania, and the National Health and Medical Research Council of Australia (NHMRC; ID# 628779), Stephanie Boldeman, the Agar family, and Ovarian Cancer Australia.