Journal article
The effects of growing up on a farm on adult lung function and allergic phenotypes: An international population-based study
B Campbell, C Raherison, CJ Lodge, AJ Lowe, T Gislason, J Heinrich, J Sunyer, F Gómez Real, D Norbäck, MC Matheson, M Wjst, J Dratva, R De Marco, D Jarvis, V Schlünssen, C Janson, B Leynaert, C Svanes, SC Dharmage
Thorax | BMJ PUBLISHING GROUP | Published : 2017
Abstract
Rationale: Evidence has suggested that exposure to environmental or microbial biodiversity in early life may impact subsequent lung function and allergic disease risk. Objectives: To investigate the influence of childhood living environment and biodiversity indicators on atopy, asthma and lung function in adulthood. Methods and measurements: The European Community Respiratory Health Survey II investigated ∼10 201 participants aged 26-54 years from 14 countries, including participants' place of upbringing (farm, rural environment or inner city) before age 5 years. A 'biodiversity score' was created based on childhood exposure to cats, dogs, day care, bedroom sharing and older siblings. Associ..
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Awarded by Medical Research Council
Funding Acknowledgements
The ECRHS study is a joint project with multiple PIs and funded by many sources. This report uses information from ECRHS I and ECRHS II PIs and research staff have changed over the years but for these phases include: Project Leader: Peter Burney; Statistician: Sue Chinn; Principal Investigator: Deborah Jarvis; Project Coordinator: Jill Knox; Principal Investigator: Christina Luczynska; Assistant Statistician: J. Potts; Data Manager: S. Arinze. Steering Committee: Josep M. Anto, Institut Municipal d'Investigac oMedica (IMIM-IMAS), Uni-versitat Pompeu Fabra (UPF); Peter Burney, Imperial College, London (Project Leader); Isa Cerveri, University of Pavia; Susan Chinn, King's College, London; Roberto de Marco, University of Verona; Thorarinn Gislason, Iceland University Hospital; Joachim Heinrich, GSF-Institute of Epidemiology; Christer Janson, Uppsala University; Deborah Jarvis, Imperial College London; Nino Kunzli, formerly University of Basel, now University of Southern California Los Angeles; Benedicte Leynaert, Institut National de la Santeet de la Recherche Medicale (INSERM); Francoise Neukirch, Institut National de la Sante et de la Recherche Medicale (INSERM); J. Schouten, University of Groningen; Jordi Sunyer, Institut Municipal d'Investigacio Medica (IMIM-IMAS), Universitat Pompeu Fabra (UPF); Cecilie Svanes, University of Bergen; Vermeire, University of Antwerp; MatthiasWjst, GSF-Institute of Epidemiology and Technical University Munchen. Principal Investigators and Senior Scientific Team: Belgium: South Antwerp & Antwerp City (P. Vermeire, J. Weyler, M. Van Sprundel, V. Nelen). Estonia: Tartu (R. Jogi, A. Soon). France: Paris (F. Neukirch, B. Leynaert, R. Liard, M. Zureik), Grenoble (I. Pin, J. Ferran-Quentin). Germany: Erfurt (J. Heinrich, M. Wjst, C. Frye, I. Meyer). Iceland: Reykjavik (T. Gislason, E. Bjornsson, D. Gislason, T. Blondal, K.B. Jorundsdottir). Italy: Turin (M. Bugiani, P. Piccioni, E. Caria, A. Carosso, E. Migliore, G. Castiglioni), Verona (R. de Marco, G. Verlato, E. Zanolin, S. Accordini, A. Poli, V. Lo Cascio, M. Ferrari), Pavia (A. Marinoni, S. Villani, M. Ponzio, F. Frigerio, M. Comelli, M. Grassi, I. Cerveri, A. Corsico). The Netherlands: Groningen & Geleen (J. Schouten, M. Kerkhof). Norway: Bergen (A. Gulsvik, E. Omenaas, C. Svanes, B. Laerum). Spain: Barcelona (J. M. Anto, J. Sunyer, M. Kogevinas, J.P. Zock, X. Basagana, A. Jaen, F. Burgos), Huelva (J. Maldonado, A. Pereira, J.L. Sanchez), Albacete (J. Martinez-Moratalla Rovira, E. Almar), Galdakao (N. Muniozguren, I. Urritia), Oviedo (F. Payo). Sweden: Uppsala (C. Janson, G. Boman, D. Norback, M. Gunnbjornsdottir), Goteborg (K. Toren, L. Lillienberg, A. C. Olin, B. Balder, A. Pfeifer-Nilsson, R. Sundberg), Umea (E. Norrman, M. Soderberg, K. Franklin, B. Lundback, B. Forsberg, L. Nystrom). Switzerland: Basel (N. Kunzli, B. Dibbert, M. Hazenkamp, M. Brutsche, U. Ackermann-Liebrich). United Kingdom: Norwich (D. Jarvis, B. Harrison), Ipswich (D. Jarvis, R. Hall, D. Seaton).