Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity

Dane M Newman; Shinya Sakaguchi; Aaron Lun; Simon Preston; Marc Pellegrini; Kseniya Khamina; Andreas Bergthaler; Stephen L Nutt; Gordon K Smyth; Anne K Voss; Tim Thomas; Wilfried Ellmeier; Gabrielle T Belz; Rhys S Allan

Journal article

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity

Dane M Newman, Shinya Sakaguchi, Aaron Lun, Simon Preston, Marc Pellegrini, Kseniya Khamina, Andreas Bergthaler, Stephen L Nutt, Gordon K Smyth, Anne K Voss, Tim Thomas, Wilfried Ellmeier, Gabrielle T Belz, Rhys S Allan

Cell Reports | CELL PRESS | Published : 2016

DOI: 10.1016/j.celrep.2016.08.056

University of Melbourne Researchers

Gabrielle Belz Author Medical Biology (W.E.H.I.)

Stephen Nutt Author Medical Biology (W.E.H.I.)

Rhys Allan Author Medical Biology (W.E.H.I.)

Dane Newman Author Medical Biology (W.E.H.I.)

Anne Voss Author Medical Biology (W.E.H.I.)

Grants

Awarded by Austrian Science Fund (FWF)

Funding Acknowledgements

We thank Lucy Sullivan and Andrew Brooks for reagents. This work was supported by grants and fellowships from the National Health and Medical Research Council of Australia (to T.T., A.K.V., M.P., S.L.N., G.K.S., G.T.B., and R.S.A.), the Australian Research Council (to S.L.N., G.T.B., and R.S.A.). Work in the laboratory of W.E. was supported by the Austrian Science Fund (FWF): P23641, P26193, P23669, and P27747. Work in the laboratory of A.B. was supported by the Austrian Science Fund (FWF): P25360. This study was made possible through the Victorian State Government Operational Infrastructure Support and Australian Government NHMRC Independent Research Institute Infrastructure Support Scheme and by the Australian Cancer Research Fund.