Journal article

Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: Ameta-analysis

JL Saver, M Goyal, A Van Der Lugt, BK Menon, CBLM Majoie, DW Dippel, BC Campbell, RG Nogueira, AM Demchuk, A Tomasello, P Cardona, TG Devlin, DF Frei, R Du Mesnil De Rochemont, OA Berkhemer, TG Jovin, AH Siddiqui, WH Van Zwam, SM Davis, C Castaño Show all

JAMA Journal of the American Medical Association | Published : 2016

Abstract

IMPORTANCE Endovascular thrombectomy with second-generation devices is beneficial for patients with ischemic stroke due to intracranial large-vessel occlusions. Delineation of the association of treatment time with outcomes would help to guide implementation. OBJECTIVE To characterize the period in which endovascular thrombectomy is associated with benefit, and the extent to which treatment delay is related to functional outcomes, mortality, and symptomatic intracranial hemorrhage. DESIGN, SETTING, AND PATIENTS Demographic, clinical, and brain imaging data aswell as functional and radiologic outcomes were pooled from randomized phase 3 trials involving stent retrievers or other second-genera..

View full abstract