Journal article
Impact of sex on prognostic host factors in surgical patients with lung cancer
Z Wainer, GM Wright, K Gough, MG Daniels, P Choong, M Conron, PA Russell, NZ Alam, D Ball, B Solomon
ANZ Journal of Surgery | WILEY | Published : 2017
DOI: 10.1111/ans.13728
Abstract
Background: Lung cancer has markedly poorer survival in men. Recognized important prognostic factors are divided into host, tumour and environmental factors. Traditional staging systems that use only tumour factors to predict prognosis are of limited accuracy. By examining sex-based patterns of disease-specific survival in non-small cell lung cancer patients, we determined the effect of sex on the prognostic value of additional host factors. Methods: Two cohorts of patients treated surgically with curative intent between 2000 and 2009 were utilized. The primary cohort was from Melbourne, Australia, with an independent validation set from the American Surveillance, Epidemiology and End Result..
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Funding Acknowledgements
Dr Zoe Wainer has been the recipient of two RACS scholarships to undertake her PhD, of which this paper is a component. In 2009, she received the Foundation for Research Scholarship and in 2010 she received the Raelene Boyle Scholarship. In 2013, The University of Melbourne Melville Hughes Scholarship has also supported her PhD.