Journal article

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments

Edwin D Hawkins, Delfim Duarte, Olufolake Akinduro, Reema A Khorshed, Diana Passaro, Malgorzata Nowicka, Lenny Straszkowski, Mark K Scott, Steve Rothery, Nicola Ruivo, Katie Foster, Michaela Waibel, Ricky W Johnstone, Simon J Harrison, David A Westerman, Hang Quach, John Gribben, Mark D Robinson, Louise E Purton, Dominique Bonnet Show all

Nature | NATURE PUBLISHING GROUP | Published : 2016

Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC) as well as a project grant from Bloodwise


Awarded by GABBA PhD program (FCT fellowship)


Awarded by Bloodwise


Awarded by Human Frontier Science Program


Awarded by CRUK


Awarded by Biotechnology and Biological Sciences Research Council


Awarded by Kay Kendall Leukaemia Fund


Awarded by European Research Council


Awarded by Cancer Research UK


Funding Acknowledgements

E.D.H. was supported by a fellowship from the European Haematology Association and an RD Wright Career fellowship from the National Health and Medical Research Council of Australia (NHMRC) as well as a project grant from Bloodwise (12033). D.D. was supported by the GABBA PhD program (FCT fellowship SFRH/BD/52195/2013). L.E.P. was supported by a National Health and Medical Research Council of Australia Senior Research Fellowship. H.Q. is supported by Victorian Cancer Agency Early Career Seed Grant. D.B., D.P. and K.F. were funded by Cancer Research UK (CRUK) and the Francis Crick Institute. C.L.C. was funded by Bloodwise (12033), Human Frontier Science Program (RGP0051/2011), CRUK (036195/41183), Biotechnology and Biological Sciences Research Council (BB/1004033/1) Kay Kendall Leukaemia Fund (KKL460) and the European Research Council (337066). We are grateful to M. Spitaler, D. Keller and L. Carlin for support with imaging. We also thank S. Piperelis, E. Ibarguen, W. Steel and H. Goyal for logistical help; A. Ivan for support from the genomics facility; J. Srivastava and C. Simpson for support from the flow cytometry facility; M. Wall for her advice on the human cytogenetics; D. Ibanez for access to software; H. Fleming, V. Greco, R. E. Sinden, S. Mostowy and P O'Donovan for critical feedback on the manuscript.