Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease
Jillian M Richmond, Dinesh S Bangari, Kingsley I Essien, Sharif D Currimbhoy, Joanna R Groom, Amit G Pandya, Michele E Youd, Andrew D Luster, John E Harris
Journal of Investigative Dermatology | ELSEVIER SCIENCE INC | Published : 2017
Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases part of the National Institutes of Health
We thank clinic patients (of JEH and AGP) for donating tissue. We thank L. Hennighausen for STAT1-floxed mice, S. Jones for K5-Cre mice, D. Kaplan for Hu-Lang-DTA mice, B.J. Longley for Krt14-Kitl* mice, U. von Andrian for DPE<SUP>GFP</SUP> mice, N. Restifo for recombinant vaccinia virus, and A. Rothstein for insightful comments on the manuscript. We thank members of the Harris Lab including P. Agarwal, M. Damiani, M. Frisoli, M. Rashighi, R. Riding, and J. Strassner for technical assistance. This study was supported by a Research Grant and Calder Research Scholar Award from the American Skin Association (to JMR); the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, under Award Numbers AR061437 and AR069114; and research grants from the Kawaja Vitiligo Research Initiative, Vitiligo Research Foundation, and Dermatology Foundation Stiefel Scholar Award (to JEH). Flow cytometry and confocal microscopy equipment used for this study is maintained by the UMMS Flow Cytometry Core Facility and Morphology Core Facility, and tissue sectioning and pathology services are maintained by the UMMS DERC Morphology Core.