Journal article

Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease

Louisa Ng, Fary Khan, Carolyn A Young, Mary Galea

COCHRANE DATABASE OF SYSTEMATIC REVIEWS | WILEY | Published : 2017

Abstract

BACKGROUND: Motor neuron disease (MND), which is also known as amyotrophic lateral sclerosis (ALS), causes a wide range of symptoms but the evidence base for the effectiveness of the symptomatic treatment therapies is limited. OBJECTIVES: To summarise the evidence from Cochrane Systematic Reviews of all symptomatic treatments for MND. METHODS: We searched the Cochrane Database of Systematic Reviews (CDSR) on 15 November 2016 for systematic reviews of symptomatic treatments for MND. We assessed the methodological quality of the included reviews using the Assessment of Multiple Systematic Reviews (AMSTAR) tool and the GRADE approach. We followed standard Cochrane study (review) selection and d..

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