Journal article

Isolation of an antimicrobial compound produced by bacteria associated with reef-building corals

Jean-Baptiste Raina, Dianne Tapiolas, Cherie A Motti, Sylvain Foret, Torsten Seemann, Jan Tebben, Bette L Willis, David G Bourne

PeerJ | PEERJ INC | Published : 2016

Abstract

Bacterial communities associated with healthy corals produce antimicrobial compounds that inhibit the colonization and growth of invasive microbes and potential pathogens. To date, however, bacteria-derived antimicrobial molecules have not been identified in reef-building corals. Here, we report the isolation of an antimicrobial compound produced by Pseudovibrio sp. P12, a common and abundant coral-associated bacterium. This strain was capable of metabolizing dimethylsulfoniopropionate (DMSP), a sulfur molecule produced in high concentrations by reef-building corals and playing a role in structuring their bacterial communities. Bioassay-guided fractionation coupled with nuclear magnetic reso..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

This work was supported by the ARC Centre of Excellence for Coral Reef Studies, AIMS@JCU, James Cook University and the Australian Institute of Marine Science. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.