Journal article

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition

Tan A Nguyen, Blake RC Smith, Michelle D Tate, Gabrielle T Belz, Marilou H Barrios, Kirstin D Elgass, Alexandra S Weisman, Paul J Baker, Simon P Preston, Lachlan Whitehead, Alexandra Garnham, Rachel J Lundie, Gordon K Smyth, Marc Pellegrini, Meredith O'Keeffe, Ian P Wicks, Seth L Masters, Craig P Hunter, Ken C Pang

Immunity | CELL PRESS | Published : 2017

Grants

Awarded by Australian NHMRC


Awarded by CASS Foundation


Awarded by US NIH


Funding Acknowledgements

We wish to thank C. Jones and A. Moseman for gifts of HSV-1 and VSV, respectively, L. Attardi, T. Okamoto, D. Huang, A. Irving, P. Gleeson, A. Janic, and J. Bernardini for gifts of plasmids, as well as J. Botros, F. Song, N. Nakatsuka, L. Mackiewicz, R. Crawley, L. Scott, C. Hay, and L. Inglis for technical assistance. We also wish to thank W. Chen, M. Zhao, N. Hacohen, N. Chevrier, M. Fleming, A. Lew, D. Miller, K. Rodgers, D. Segal, and all members of the Hunter, Masters, and Wicks laboratories for helpful discussions and comments. K.C.P., T.A.N., B.R.C.S., and M.H.B. are supported by the Australian NHMRC (ID 520574 and 1064591), Royal Australasian College of Physicians, Menzies Foundation, CASS Foundation (SM13-4846 and SM14-5566), and Reid Family Trust. M.D.T. was supported by the Australian NHMRC (Fellowship #1123319). M.P. was supported by Australian NHMRC (Grants 1006592, 1045549, and 1065626), The Sylvia & Charles Viertel Senior Medical Research Fellowship, the Victorian State Government Operational Infrastructure Support, and the Independent Research Institutes Infrastructure Support Scheme (NHMRC). S.L.M. receives funding from GlaxoSmithKline. A.S.W. and C.P.H. are supported by the US NIH (1R01GM089795 and U19CA179513).