Journal article
Can EEG differentiate among syndromes in genetic generalized epilepsy?
U Seneviratne, G Hepworth, M Cook, W D'Souza
Journal of Clinical Neurophysiology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2017
Abstract
Purpose: To evaluate EEG differences among syndromes in genetic generalized epilepsy based on quantified data. Methods: Twenty-four-hour ambulatory EEGs were recorded in consecutive patients diagnosed with genetic generalized epilepsy. All epileptiform EEG abnormalities were quantified into density scores (total duration of epileptiform discharges per hour). One-way analysis of variance was conducted to find out differences in EEG density scores among the syndromes. Generalized linear mixed models were also fitted to explore the association between the proportion of "pure" generalized spike-wave paroxysms and fragments (without intervening polyspikes/polyspike-waves) and the syndromes. Resul..
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Funding Acknowledgements
U. Seneviratne has received travel and speaker honoraria from UCB Pharma. W. D'Souza has received grants and personal fees from UCB Pharma, grants and personal fees from Eisai Pharmaceuticals, and fees from SciGen Pharmaceuticals during the conduct of the study. M. Cook has received speaker honoraria from UCB Pharma and Sanofi Australia and travel honoraria from UCB Pharma and SciGen. He has received research grants from the National Health and Medical Research Council (Australia) and the Australian Research Council. He has also received a Science, Technology, and Innovation Grant from the State Government of Victoria, Australia. The remaining author has no funding or conflicts of interest to disclose.