The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases
Matthias Schmitz, Maria Cramm, Franc Llorens, Dominik Mueller-Cramm, Steven Collins, Ryuichiro Atarashi, Katsuya Satoh, Christina D Orru, Bradley R Groveman, Saima Zafar, Walter J Schulz-Schaeffer, Byron Caughey, Inga Zerr
Nature Protocols | NATURE PUBLISHING GROUP | Published : 2016
Related Projects (1)
DETERMINING NORMAL PRION PROTEIN FUNCTION, EMPHASISING THE ROLE PLAYED BY PROTEIN CLEAVAGE, AND ALSO DEFINING THE RELATIONSHIP BETWEEN SURVEILLANCE INTENSITY AND ANNUAL SPORADIC CJD INCIDENCE
As a neurologist undertaking research into prion diseases over an extended period, I have been able to lead and participate in many projects..
Awarded by EU Joint Program-Neurodegenerative Disease Research (JPND-DEMTEST (Biomarker-based diagnosis of rapid progressive dementias-optimization of diagnostic protocols)
Awarded by Robert Koch Institute through Federal Ministry of Health
Awarded by NHMRC Practitioner Fellowship
Awarded by Grants-in-Aid for Scientific Research
Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
This study was performed as part of the Clinical Dementia Center at the University Medical Center Gottingen and was partly supported by grants from the EU Joint Program-Neurodegenerative Disease Research (JPND-DEMTEST (Biomarker-based diagnosis of rapid progressive dementias-optimization of diagnostic protocols, 01ED1201A) and by the Robert Koch Institute through funds from the Federal Ministry of Health (grant no. 1369341). This work was also supported in part by the Intramural Research Program of the NIAID. S.C. is supported by a NHMRC Practitioner Fellowship (identification no. APP1005816) and by the Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR), which is funded by the Commonwealth Department of Health.